Frederick J Fricker

Frederick J Fricker, M.D.

Eminent Scholar & Professor

Department: MD-COGNITAL HRT CTR EXCELLENCE
Business Phone: (352) 273-7770
Business Email: frickfj@peds.ufl.edu

About Frederick J Fricker

F. Jay Fricker, MD, is board-certified in general pediatrics and pediatric cardiology. He led the pediatric cardiology division at the University of Florida College of Medicine from his arrival in 1995 until 2014. Dr. Fricker was instrumental in establishing the UF Health Congenital Heart Center in 2006, serving as its medical director through 2014, and in making the center among the top congenital heart programs in the country. 

He received his medical degree from Loyola University Chicago Stritch School of Medicine and completed his pediatric residency and his pediatric cardiology fellowship at the Children’s Hospital of Pittsburgh and the University of Pittsburgh Medical Center.

Dr. Fricker’s clinical interests focus on the nonsurgical aspects of pediatric heart and lung transplantation and on treating patients with pulmonary hypertension. His research has focused on immune-suppression strategies after heart transplantation in children. Widely recognized for his expertise in pediatric heart/heart-lung transplantation, Dr. Fricker has been a visiting professor and guest lecturer throughout the country and world.

Dr. Fricker has a major interest in global health, and he has been appointed as co-director of the pediatric resident global health track at the UF College of Medicine. He also serves on the board of directors of Amazon Vision ministries; reviews medical records for Little Hearts Medical on Chinese orphans with congenital heart disease pending adoption by U.S. families and has participated in cardiology/cardiovascular surgical missions sponsored by the Palestinian Children’s Relief Fund (PCRF) in the West Bank and Gaza.

Dr. Fricker also serves on the Medical Selection Committee of the UF College of Medicine. His memberships include the American Academy of Pediatrics, Section of Pediatric Cardiology; American Pediatrics Society; International Society for Heart and Lung Transplantation; and the American Heart Association Council on Cardiovascular Diseases in the Young.

Board Certifications

  • Pediatrics
    American Board of Pediatrics

Clinical Profile

Specialties
  • Pediatrics
Subspecialties
  • Pediatric Cardiology
Areas of Interest
  • Congenital heart disease
  • Heart transplant
  • Hypoplastic left heart syndrome
  • Lung transplant
  • Pediatric Cardiology
  • Pulmonary hypertension
  • Transplant rejection
  • Transplant services

Publications

2021
Combined Hybrid Procedure and VAD insertion in 9 High-Risk Neonates and Infants with HLHS.
The Annals of thoracic surgery. [DOI] 10.1016/j.athoracsur.2021.05.073. [PMID] 34186096.
2021
Support with extracorporeal membrane oxygenation for over 1 year duration as a bridge to cardiac transplantation: a case report and review of the literature.
Cardiology in the young. 31(9):1495-1497 [DOI] 10.1017/S1047951121003656. [PMID] 34538285.
2019
Thenar Muscle Oxygen Saturation Using Vascular Occlusion Test: A Novel Technique to Study Microcirculatory Abnormalities in Pediatric Heart Failure Patients.
Pediatric cardiology. 40(6):1151-1158 [DOI] 10.1007/s00246-019-02118-y. [PMID] 31098675.
2018
End-organ recovery post-ventricular assist device can prognosticate survival.
Journal of critical care. 44:57-62 [DOI] 10.1016/j.jcrc.2017.10.017. [PMID] 29065351.
2018
Heart Transplant in Patient With Isolated Left Superior Vena Cava by Atrial Appendage Rotation.
The Annals of thoracic surgery. 105(6):e279-e281 [DOI] 10.1016/j.athoracsur.2018.01.008. [PMID] 29410126.
2018
Heart Transplantation for Adult Congenital Heart Disease: Overview and Special Considerations
Cardiovascular Innovations and Applications. 3(1):73-84 [DOI] 10.15212/CVIA.2017.0043.
2017
Double-outlet right ventricle revisited.
The Journal of thoracic and cardiovascular surgery. 154(2):598-604 [DOI] 10.1016/j.jtcvs.2017.03.049. [PMID] 28528718.
2015
Elevated pre-transplant pulmonary vascular resistance is not associated with mortality in children without congenital heart disease: a multicenter study.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 34(3):448-56 [DOI] 10.1016/j.healun.2014.04.021. [PMID] 24906793.
2014
Ventricular septal defect.
Orphanet journal of rare diseases. 9 [DOI] 10.1186/s13023-014-0144-2. [PMID] 25523232.
2012
Is Adolescence An Independent Risk Factor for Rejection in Pediatric Heart Transplantation, Independent of Age At Listing?
Journal of Heart and Lung Transplantation. 31:S138-S139
2012
Virus-Derived Immunomodulatory Therapeutics for Heart Transplantation
Journal of Heart and Lung Transplantation. 31
2011
Use of 320-detector computed tomographic angiography for infants and young children with congenital heart disease.
Pediatric cardiology. 32(4):426-32 [DOI] 10.1007/s00246-010-9873-8. [PMID] 21210093.
2010
Decline in Rejection in the First Year After Pediatric Cardiac Transplantation: a Multi-Institutional Study
Journal of Heart and Lung Transplantation. 29(6):625-632 [DOI] 10.1016/j.healun.2009.12.009. [PMID] 20207171.
2010
Effect of IVIG administration on complement activation and HLA antibody levels.
Transplant international : official journal of the European Society for Organ Transplantation. 23(10):1015-22 [DOI] 10.1111/j.1432-2277.2010.01088.x. [PMID] 20412537.
2010
Post-transplant lymphoproliferative disorder in children: recent outcomes and response to dual rituximab/low-dose chemotherapy combination.
Pediatric transplantation. 14(7):896-902 [DOI] 10.1111/j.1399-3046.2010.01370.x. [PMID] 20642490.
2010
Post-Transplant Lymphoproliferative Disorders in Children: Recent Outcomes and Response To Dual Rituximab/Chemotherapy Combination
American Journal of Transplantation. 10
2010
Post-Transplant Lymphoproliferative Disorders in Children: Recent Outcomes and Response To Dual Rituximab/Chemotherapy Combination
American Journal of Transplantation. 10
2009
Aortic aneurysms and dissection diagnosed by computed tomography 19 years after repair of coarctation.
Cardiology in the young. 19(4):398-9 [DOI] 10.1017/S1047951109990242. [PMID] 19476694.
2009
Decline in Rejection Hi the First Year After Pediatric Cardiac Transplantation: a Multi-Institutional Study
Journal of Heart and Lung Transplantation. 28
2009
Evaluating the extracardiac Fontan conduit by multislice computed tomography: an emerging modality.
Cardiology in the young. 19(2):204-5 [DOI] 10.1017/S1047951109003783. [PMID] 19224676.
2009
Post-Transplant Lymphoproliferative Disorder in Children: Recent Clinical Characteristics, Outcomes and Response To Dual Rituximab/Chemotherapy Combination
American Journal of Transplantation. 9
2008
Anti-Cd20 Monoclonal Antibody (Rituximab) for Refractory Post-Transplant Lymphoproliferative Disorders (Ptld) in Children: Final Results of a Phase Ii Multi-Center Clinical Trial
American Journal of Transplantation. 8:308-309
2008
Ventricular assist device implantation in the pediatric population: does pump size selection and associated hemodynamics impact outcomes?
ASAIO journal (American Society for Artificial Internal Organs : 1992). 54(5):474-8 [DOI] 10.1097/MAT.0b013e3181888f2d. [PMID] 18812736.
2007
Biomedical and psychosocial evaluation of “cured” adults with congenital heart disease.
Congenital heart disease. 2(1):44-54 [DOI] 10.1111/j.1747-0803.2007.00071.x. [PMID] 18377516.
2006
Increased myocardial performance index correlates with biopsy-proven rejection in pediatric heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 25(1):61-6 [PMID] 16399532.
View on: PubMed
2006
Lymphoproliferative disorders after paediatric heart transplantation: a multi-institutional study.
Lancet (London, England). 367(9506):233-9 [PMID] 16427492.
View on: PubMed
2005
An institutional review of the value of computed tomographic angiography in the diagnosis of congenital cardiac malformations.
Cardiology in the young. 15(1):47-51 [PMID] 15831161.
View on: PubMed
2005
Genetic linkage of a novel autosomal dominant restrictive cardiomyopathy locus.
Journal of medical genetics. 42(8):663-5 [PMID] 16061566.
View on: PubMed
2003
Toxic serum trough concentrations after administration of nebulized tobramycin.
Pharmacotherapy. 23(4):543-5 [PMID] 12680485.
View on: PubMed
2001
Clinical and molecular studies of a large family with desmin-associated restrictive cardiomyopathy.
Clinical genetics. 59(4):248-56 [PMID] 11298680.
View on: PubMed
2001
Safety and efficacy of pravastatin therapy for the prevention of hyperlipidemia in pediatric and adolescent cardiac transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 20(6):611-8 [PMID] 11404165.
View on: PubMed
2000
Balloon aortic valvotomy through a carotid cutdown in infants with severe aortic stenosis: results of the multi-centric registry.
Cardiology in the young. 10(3):225-32 [PMID] 10824903.
View on: PubMed
2000
Glucocorticoid-induced osteopenia in adolescent heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 19(9):840-5 [PMID] 11008072.
View on: PubMed
2000
Increased expression of the lymphocyte early activation marker CD69 in peripheral blood correlates with histologic evidence of cardiac allograft rejection.
Transplantation. 69(10):2102-7 [PMID] 10852605.
View on: PubMed
2000
Metabolic aspects of myocardial disease and a role for L-carnitine in the treatment of childhood cardiomyopathy.
Pediatrics. 105(6):1260-70 [PMID] 10835067.
View on: PubMed
1999
Dobutamine stress echocardiography: experience in pediatric heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 18(7):725-32 [PMID] 10452350.
View on: PubMed
1999
Heart transplantation in children: indications. Report of the Ad Hoc Subcommittee of the Pediatric Committee of the American Society of Transplantation (AST).
Pediatric transplantation. 3(4):333-42 [PMID] 10562980.
View on: PubMed
1999
Tacrolimus-based triple-drug immunosuppression minimizes serum lipid elevations in pediatric cardiac transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 18(7):707-13 [PMID] 10452348.
View on: PubMed
1999
Transcatheter closure of modified Blalock-Taussig shunt with Gianturco-Grifka Vascular Occlusion Device.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 48(4):365-7 [PMID] 10559814.
View on: PubMed
1998
Clinical relevance of in vitro propagation of activated lymphocytes from endomyocardial biopsy samples of pediatric heart transplant recipients.
Pediatric transplantation. 2(3):200-5 [PMID] 10084743.
View on: PubMed
1997
Long-term survivors of pediatric heart transplantation: a multicenter report of sixty-eight children who have survived longer than five years.
The Journal of pediatrics. 130(6):862-71 [PMID] 9202606.
View on: PubMed
1997
New-onset diabetes mellitus in pediatric thoracic organ recipients receiving tacrolimus-based immunosuppression.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 16(3):275-82 [PMID] 9087870.
View on: PubMed
1997
Posttransplantation lymphoproliferative disorders in pediatric thoracic organ recipients.
The Journal of pediatrics. 131(2):309-13 [PMID] 9290623.
View on: PubMed
1996
A prospective trial of tacrolimus (FK 506) in clinical heart transplantation: intermediate-term results.
The Journal of thoracic and cardiovascular surgery. 111(4):764-72 [PMID] 8614136.
View on: PubMed
1996
Experience of FK506 immune suppression in pediatric heart transplantation: a study of long-term adverse effects.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 15(4):415-22 [PMID] 8732602.
View on: PubMed
1996
Interferon-alpha affects the immune response in post-transplant lymphoproliferative disorder.
American journal of respiratory and critical care medicine. 153(4 Pt 1):1442-7 [PMID] 8616579.
View on: PubMed
1996
Mitochondrial function in children with idiopathic dilated cardiomyopathy.
Journal of inherited metabolic disease. 19(3):309-12 [PMID] 8803773.
View on: PubMed
1996
Specific mitochondrial DNA deletions in idiopathic dilated cardiomyopathy.
Cardiovascular research. 31(2):306-13 [PMID] 8730408.
View on: PubMed
1995
Chronic rejection in heart-lung transplant recipients: the relationship between obliterative bronchiolitis and coronary artery disease.
Transplantation proceedings. 27(1):1288-9 [PMID] 7878885.
View on: PubMed
1995
Critical issues in pediatric lung transplantation.
The Journal of thoracic and cardiovascular surgery. 109(1):60-4; discussion 64 [PMID] 7815808.
View on: PubMed
1995
Exercise testing in pediatric heart, heart-lung, and lung transplant recipients.
Chest. 107(5):1328-35 [PMID] 7750327.
View on: PubMed
1995
Immunosuppression switch in pediatric heart transplant recipients: cyclosporine to FK 506.
Journal of the American College of Cardiology. 25(5):1183-8 [PMID] 7534779.
View on: PubMed
1995
Occult restrictive hemodynamics after pediatric heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 14(6 Pt 1):1109-15 [PMID] 8719458.
View on: PubMed
1994
Acute myocarditis. Rapid diagnosis by PCR in children.
Circulation. 90(1):330-9 [PMID] 8026015.
View on: PubMed
1994
Cardiac transplantation at the University of Pittsburgh: 1994 update.
Clinical transplants. 121-5 [PMID] 7547531.
View on: PubMed
1994
Experience with pediatric lung transplantation.
The Journal of pediatrics. 124(2):261-8 [PMID] 8301434.
View on: PubMed
1994
Extracorporeal membrane oxygenation support as a bridge to pediatric heart transplantation.
Circulation. 90(5 Pt 2):II66-9 [PMID] 7955285.
View on: PubMed
1994
Orthotopic heart transplantation in children with congenital heart disease.
The Annals of thoracic surgery. 58(6):1664-9 [PMID] 7979732.
View on: PubMed
1994
Posttransplant coronary artery disease in children. A multicenter national survey.
Circulation. 90(5 Pt 2):II56-60 [PMID] 7955283.
View on: PubMed
1994
Role of right ventricular endomyocardial biopsy in infants and children with suspected or possible myocarditis.
British heart journal. 72(4):360-3 [PMID] 7833195.
View on: PubMed
1993
24th Bethesda conference: Cardiac transplantation. Task Force 1: Organization of heart transplantation in the U.S.
Journal of the American College of Cardiology. 22(1):8-14 [PMID] 8509567.
View on: PubMed
1993
A decade (1982 to 1992) of pediatric cardiac transplantation and the impact of FK 506 immunosuppression.
The Journal of thoracic and cardiovascular surgery. 105(3):464-72; discussion 472 [PMID] 7680396.
View on: PubMed
1993
Improved survival following pediatric cardiac transplantation in high-risk patients.
Circulation. 88(5 Pt 2):II218-23 [PMID] 8222157.
View on: PubMed
1993
Pediatric lung transplantation. The years 1985 to 1992 and the clinical trial of FK 506.
The Journal of thoracic and cardiovascular surgery. 105(2):337-45; discussion 346 [PMID] 7679172.
View on: PubMed
1993
Pediatric lung transplantation: expanding indications, 1985 to 1993.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 12(6 Pt 2):S246-54 [PMID] 8312344.
View on: PubMed
1993
Pediatric retransplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 12(6 Pt 2):S319-27 [PMID] 8312351.
View on: PubMed
1992
Toxoplasmosis in pediatric recipients of heart transplants.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 14(4):847-51 [PMID] 1576279.
View on: PubMed
1991
A clinical trial of FK 506 as primary and rescue immunosuppression in cardiac transplantation.
Transplantation proceedings. 23(1 Pt 2):1149-52 [PMID] 1703336.
View on: PubMed
1991
Cardiac transplantation in children.
Perspectives in pediatric pathology. 14:60-93 [PMID] 2038549.
View on: PubMed
1991
Guidelines for pediatric therapeutic cardiac catheterization. A statement for health professionals from the Committee on Congenital Cardiac Defects of the Council on Cardiovascular Disease in the Young, the American Heart Association.
Circulation. 84(5):2248-58 [PMID] 1934396.
View on: PubMed
1991
Posttransplant lymphoproliferative disease in thoracic organ transplant patients: ten years of cyclosporine-based immunosuppression.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 10(6):877-86; discussion 886 [PMID] 1661607.
View on: PubMed
1991
Preliminary experience with FK506 in thoracic transplantation.
Transplantation. 52(1):164-7 [PMID] 1713363.
View on: PubMed
1991
Session VII: Physiologic and psychological growth and development in pediatric heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 10(5 Pt 2):848-55 [PMID] 1720661.
View on: PubMed
1991
The clinical trial of FK 506 as primary and rescue immunosuppression in pediatric cardiac transplantation.
Transplantation proceedings. 23(6):3058-60 [PMID] 1721359.
View on: PubMed
1990
Coronary arteriosclerosis in pediatric heart transplant survivors: limitation of long-term survival.
The Journal of pediatrics. 116(2):177-83 [PMID] 2299487.
View on: PubMed
1990
Heart transplantation in patients with malignant disease.
The Journal of heart transplantation. 9(6):627-9; discussion 630 [PMID] 2277299.
View on: PubMed
1990
Pediatric cardiac transplantation.
Cardiovascular clinics. 20(2):223-35 [PMID] 2404601.
View on: PubMed
1990
Usefulness of the internal jugular venous route for cardiac catheterization in children.
The American journal of cardiology. 65(18):1276-8 [PMID] 2337045.
View on: PubMed
1989
Cardiac transplantation in children.
Cardiology clinics. 7(2):411-8 [PMID] 2659182.
View on: PubMed
1989
Extracorporeal membrane oxygenation for postcardiotomy cardiogenic shock in children.
The Annals of thoracic surgery. 47(6):903-6 [PMID] 2757447.
View on: PubMed
1989
Infections in pediatric orthotopic heart transplant recipients.
The Pediatric infectious disease journal. 8(2):87-93 [PMID] 2649868.
View on: PubMed
1989
Lessons learned in pediatric heart transplantation.
The Annals of thoracic surgery. 48(5):617-22; discussion 622 [PMID] 2818048.
View on: PubMed
1988
Late follow-up of children after heart transplantation.
Transplantation proceedings. 20(1 Suppl 1):743-6 [PMID] 3279665.
View on: PubMed
1987
Cyclosporine kinetics in pediatric patients with congestive heart failure.
Transplantation proceedings. 19(1 Pt 2):1528-9 [PMID] 3274373.
View on: PubMed
1987
Experience with heart transplantation in children.
Pediatrics. 79(1):138-46 [PMID] 3540834.
View on: PubMed
1985
Echocardiographic findings before and after liver transplantation.
The American journal of cardiology. 55(11):1373-8 [PMID] 3887884.
View on: PubMed
1985
Successful dilatation of a stenotic Blalock-Taussig anastomosis by percutaneous transluminal balloon angioplasty.
The American journal of cardiology. 55(6):861-2 [PMID] 3156488.
View on: PubMed
1985
Ventricular septal defect associated with aneurysm of the membranous septum.
Journal of the American College of Cardiology. 5(1):118-23 [PMID] 3964798.
View on: PubMed
1984
Surgical management of univentricular heart with subaortic obstruction.
The Annals of thoracic surgery. 37(5):417-21 [PMID] 6712345.
View on: PubMed
1983
Congestive heart failure and absent femoral pulses in newborns without coarctation of the aorta.
Chest. 83(4):688-90 [PMID] 6831958.
View on: PubMed
1983
Hemodynamic function after the Mustard operation for transposition of the great arteries.
The American journal of cardiology. 51(9):1514-9 [PMID] 6846186.
View on: PubMed
1983
The anatomical heterogeneity of hearts lacking a patent communication between the left atrium and the ventricular mass (‘mitral atresia’) in presence of a patent aortic valve.
European heart journal. 4(7):477-86 [PMID] 6628425.
View on: PubMed
1983
Unilateral pulmonary vein atresia: clinical and radiographic spectrum.
Pediatric cardiology. 4(2):105-12 [PMID] 6878066.
View on: PubMed
1980
Absent right superior vena cava with persistent left superior vena cava: implications and management.
The American journal of cardiology. 45(1):117-22 [PMID] 7350758.
View on: PubMed
1980
Coarctation of the aorta in children. Late results after surgery.
American journal of diseases of children (1960). 134(5):464-6 [PMID] 7377153.
View on: PubMed
1980
Left atrioventricular valve atresia: clinical management.
Circulation. 61(1):123-7 [PMID] 7349925.
View on: PubMed
1979
Anomalous left pulmonary artery: successful management.
The Journal of thoracic and cardiovascular surgery. 77(5):748-52 [PMID] 431111.
View on: PubMed
1979
Iliac venous thrombosis in infants and children after cardiac catheterization.
Catheterization and cardiovascular diagnosis. 5(1):67-74 [PMID] 455429.
View on: PubMed
1979
Pneumonectomy for intractable left bronchial compression in d-transposition of the great arteries.
The Journal of thoracic and cardiovascular surgery. 77(2):212-6 [PMID] 762961.
View on: PubMed
1978
Clinical implications of postoperative unilateral phrenic nerve paralysis.
The Journal of thoracic and cardiovascular surgery. 76(3):297-304 [PMID] 682661.
View on: PubMed
1978
Clinical use of blade atrial septostomy.
Circulation. 58(4):600-6 [PMID] 688569.
View on: PubMed
1978
Echocardiographic and hemodynamic correlation in transposition of the great arteries.
Circulation. 57(2):291-8 [PMID] 618617.
View on: PubMed
1977
Valve replacement in children and adolescents.
The Journal of thoracic and cardiovascular surgery. 73(6):872-6 [PMID] 870765.
View on: PubMed

Education

Fellowship – Pediatric Cardiology
1977 · Children’s Hospital of Pittsburgh
Residency – Pediatrics
1973 · Children’s Hospital of Pittsburgh
Internship
1971 · Mercy Hospital
Medical Degree
1970 · Loyola University

Teaching Profile

Courses Taught
2018
MDC7400 Pediatric Clerkship
2018
BMS6300 Fund Micro and Immuno
2013-2016
MDT7400 Elect Top/Pediatrics
2010-2013
MEL7937 Elect Top/Pediatrics

Contact Details

Phones:
Business:
(352) 273-7770
Emails: